CEE PG MDMS Nepal 2023/24 2080 Previous year Questions

MEC Common Entrance Exam (MD/MS) 2023

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MEDICINE
1. A patient has prolonged PT/INR and obstructive jaundice. His PT/INR is likely to improve after administration of:
  • a. Vitamin K
  • b. Heparin
  • c. High-fat diet
  • d. Platelet transfusion
Correct Answer: a
2. In an adult with a normal lung function, oxygen therapy is most useful in:
  • a. Altitude sickness
  • b. Decompression sickness
  • c. Anemia
  • d. Hemorrhage
Correct Answer: a
3. HbsAg positive only with all other normal serological markers indicates:
  • a. Acute hepatitis
  • b. Chronic Hepatitis
  • c. Incubation period
  • d. Super carrier
Correct Answer: c
4. Increased sweat chloride is seen in which of the following conditions?
  • a. Bronchiectasis
  • b. Cystic fibrosis
  • c. ABPA
  • d. Tuberculosis
Correct Answer: b
5. Hemoptysis is a characteristic feature of:
  • a. Mitral stenosis
  • b. Pulmonary stenosis
  • c. Aortic stenosis
  • d. Tricuspid stenosis
Correct Answer: a
6. All are true in iron deficiency anemia EXCEPT:
  • a. Decreased serum ferritin
  • b. Decreased TIBC
  • c. Decreased transferrin saturation
  • d. Decreased serum Iron
Correct Answer: b
7. The most sensitive test for diagnosis of DIC is:
  • a. D-dimer
  • b. Increased FDP
  • c. Prolonged PT and pTT
  • d. Thrombocytopenia
Correct Answer: b
8. All are manifestations of increased portal pressure in portal hypertension EXCEPT:
  • a. Hepatomegaly
  • b. Splenomegaly
  • c. Ascites
  • d. Hemorrhoids
Correct Answer: a
9. A patient presented with fever, night sweats, and B/L facial nerve palsy. Examination revealed leukocytosis, erythema nodosum and bilateral hilar lymphadenopathy. The most probable diagnosis is:
  • a. Sarcoidosis
  • b. Tuberculosis
  • c. Lymphoma
  • d. Hypersensitivity pneumonitis
Correct Answer: a
10. Which of the following causes secondary hyperparathyroidism?
  • a. Chronic renal failure
  • b. Heart failure
  • c. Liver failure
  • d. Respiratory failure
Correct Answer: a
11. In the case of hyperkalemia, which of the following will facilitate potassium removal from the body?
  • a. Calcium gluconate
  • b. Insulin with dextrose
  • c. Furosemide
  • d. Salbutamol
Correct Answer: c
12. Which of the following is a late feature of acromegaly?
  • a. Increased ICP
  • b. Visual defects
  • c. Coarse facial features
  • d. Overgrowth of maxilla and mandible
Correct Answer: c
13. The correct statement about polycythemia is:
  • a. Elevated erythropoietin suggests diagnosis is unlikely
  • b. It commonly transforms into acute leukemia
  • c. Aspirin is given lifelong to prevent thrombosis
  • d. Increased risk of thrombosis is seen in thrombocytosis
Correct Answer: a
14. An icteric patient with cirrhosis has a distended abdomen, a fever of 100-102°F, and abdominal pain. On ascitic tapping, 500 mL of fluid was drained out. Ascitic fluid cytology shows gram-negative bacilli. What is the diagnosis?
  • a. Spontaneous bacterial peritonitis
  • b. Subacute intestinal obstruction
  • c. Diverticulitis
  • d. Appendicitis
Correct Answer: a
15. Investigation of choice for patients with a high likelihood of pulmonary embolism is:
  • a. D-dimer
  • b. CT angiography
  • c. Chest X-ray
  • d. FDP
Correct Answer: b
16. A middle-aged man came to your OPD with complaints of hyperpigmentation over the nape of the neck and axilla. Which investigation would you prefer next?
  • a. Cortisol
  • b. TSH
  • c. Melanin level
  • d. Blood glucose
Correct Answer: d
17. For a person diagnosed with DVT under warfarin therapy, INR should be maintained in the range of:
  • a. 1-2
  • b. 2-3
  • c. 1.5-2.5
  • d. 2-4
Correct Answer: b
18. Somatostatin analogs are used in the treatment of:
  • a. Bleeding esophageal varices
  • b. Zollinger Ellison syndrome
  • c. Peptic ulcer disease
  • d. Constipation
Correct Answer: a
SURGERY
19. Spastic neurogenic bladder is due to:
  • a. Denervation
  • b. Bladder tumor
  • c. Deafferentation
  • d. Spinal cord injury
Correct Answer: d
20. Treatment of Grade II hemorrhoids in 3, 7 and 11 O'clock is:
  • a. Sitz bath and stool softeners
  • b. Banding
  • c. Cryosurgery
  • d. Sclerotherapy
Correct Answer: b
21. A 68-year-old male with an indirect inguinal hernia. Maximum systemic symptoms are present if the hernia is:
  • a. Incarcerated
  • b. Strangulated
  • c. Irreducible
  • d. Obstructed
Correct Answer: b
22. A 67-year-old male with BPH S/P TURP complaints of vomiting and drowsiness. What is the likely cause?
  • a. Water intoxication
  • b. Sepsis
  • c. Hepatic coma
  • d. Hypernatremia
Correct Answer: a
23. Noninflammatory visceral pain is due to:
  • a. Acute cholecystitis
  • b. Mesenteric ischemia
  • c. Inflammatory bowel disease
  • d. Acute appendicitis
Correct Answer: b
24. Germinal membrane of hydatid cyst is:
  • a. Endocyst
  • b. Ectocyst
  • c. Pericyst
  • d. Epicyst
Correct Answer: a
25. Mass coming out of the rectum during defecation and going back spontaneously. It is grade........of internal hemorrhoids.
  • a. I
  • b. II
  • c. III
  • d. IV
Correct Answer: b
26. Ranson criteria in acute pancreatitis is used to access:
  • a. Stage of disease
  • b. Discharge
  • c. Severity
  • d. Admission
Correct Answer: c
27. A 27-year-old female complains of lower back pain which is dull in nature. On examination, renal angle tenderness is positive. A kidney stone is seen on USG at the pelviureteric junction. X-ray KUB is normal. The most likely stone in the patient is:
  • a. Calcium oxalate
  • b. Uric acid
  • c. Staghorn calculus
  • d. Calcium phosphate
Correct Answer: b
28. A 25-year-old male after RTA complains of testicular pain. On examination, the scrotum was swollen with overlying erythema. The most likely diagnosis is:
  • a. Testicular torsion
  • b. Hematocele
  • c. Hydrocele
  • d. Varicocele
Correct Answer: b
29. Gas used for creating pneumoperitoneum is:
  • a. Oxygen
  • b. CO2
  • c. Nitrogen
  • d. Hydrogen
Correct Answer: b
30. A 12-year-old child presents to your OPD. On examination, Murphy's sign was positive. This is seen in:
  • a. Acute cholecystitis
  • b. Choledocholithiasis
  • c. Gall bladder carcinoma
  • d. Pancreatic head carcinoma
Correct Answer: a
31. Obstructive jaundice causing biliary tract compression is due to posterior growth of:
  • a. Tumor of head of pancreas
  • b. Tumor of tail of pancreas
  • c. Duodenal adenocarcinoma
  • d. Carcinoma stomach
Correct Answer: a
32. ERCP is indicated for:
  • a. CBD stone
  • b. Gallstones
  • c. Acute pancreatitis
  • d. Acute cholecystitis
Correct Answer: a
33. Vitamin K is preferred in which condition that will help to halt the progression of the disease?
  • a. Acute cholecystitis
  • b. Diaphragmatic hernia
  • c. Obstructive jaundice
  • d. Cholelithiasis
Correct Answer: c
34. Iodine therapy is given prior to subtotal thyroidectomy in Grave's disease. The reason behind this is:
  • a. Reduces vascularity of thyroid gland
  • b. To make euthyroid state before surgery
  • c. To provide thyroid supplementation
  • d. To decrease postoperative complications
Correct Answer: a
35. Triple regimen for Helicobacter pylori includes all of the following EXCEPT:
  • a. Clarithromycin
  • b. Pantoprazole
  • c. Cefixime
  • d. Amoxicillin
Correct Answer: c
36. Mallory Weiss tear site is:
  • a. Thoracic part of the esophagus
  • b. Gastroesophageal junction
  • c. Gastroduodenal junction
  • d. Second part of duodenum
Correct Answer: b
OBSTETRICS AND GYNECOLOGY
37. A 34-year-old female at 12 WOG made an appointment for counseling in Gynae OPD with her husband. During her first normal delivery, there was a 3rd-degree perineal tear with the tear of the anal sphincter for which repair was done. She is worried about the second delivery and concerned about the mode of delivery this time. The best approach is:
  • a. Normal delivery
  • b. Forceps delivery
  • c. Vacuum delivery
  • d. Elective CS
Correct Answer: d
38. A rural PHC conducted a camp for a female of reproductive age for cervical cancer screening. Acetowhite areas were seen on VIA. The next line of management is:
  • a. Refer to higher center
  • b. Screen and treat
  • c. Biopsy and follow-up with histopathology reports
  • d. Hysterectomy
Correct Answer: c
39. What will be the color change with acetic acid in cervical cancer?
  • a. Yellow
  • b. Pink
  • c. White
  • d. Blue
Correct Answer: c
40. The most common cause of death of women postpartum in Nepal is:
  • a. Infection
  • b. Hemorrhage
  • c. Trauma
  • d. Seizure
Correct Answer: b
41. Investigation of choice in case of ectopic pregnancy is:
  • a. Transvaginal sonography
  • b. Laparoscopy
  • b. USG
  • d. Beta hCG
Correct Answer: a
42. Mechanism of action of CuT:
  • a. Prevents ovulation
  • b. Prevents fertilization
  • c. Blastocidal
  • d. Spermicidal
Correct Answer: d
43. A postpartum lady complains of mild fever and shivering. Which drug is responsible for this?
  • a. Oxytocin
  • b. Misoprostol
  • c. Ergometrine
  • d. IV fluids
Correct Answer: b
44. A 36-year-old female complained of intense pruritus with curdy white vaginal discharge which was not improved by genital hygiene. Most probable diagnosis is:
  • a. Bacterial vaginosis
  • b. Trichomonas
  • c. Vulvovaginal candidiasis
  • d. Gonorrhea
Correct Answer: c
45. A 37-year-old pregnant lady at 34 WOG presents with painless vaginal bleeding. She had similar episodes 1 week before. The most likely diagnosis is:
  • a. Placenta previa
  • b. Abruptio placenta
  • c. Threatened abortion
  • d. Missed abortion
Correct Answer: a
46. During normal labor, 10 units of oxytocin were given but the placenta could not be removed 40 minutes post-delivery. There are no signs of separation. What is your next step?
  • a. Add 5 units of oxytocin IM
  • b. Add 40 units of oxytocin in 500 ml NS and give it over 25 minutes
  • c. Manual removal of placenta
  • d. Wait for spontaneous removal
Correct Answer: c
47. A G2P1L1 female at 30 WOG with preeclampsia has a history of asthma. Her blood pressure remained elevated even after the delivery. Which of the antihypertensive medicines can be given?
  • a. Nifedipine
  • b. Labetalol
  • c. Amlodipine
  • d. Enalapril
Correct Answer: a
48. A 30-year-old G2P1 into her 3 months of pregnancy presents with symptoms of heat intolerance. There is low TSH, high T3, and high T4. The drug of choice for this case is:
  • a. Propylthiouracil
  • b. Methimazole
  • c. Propranolol
  • d. Radioactive iodine
Correct Answer: a
PEDIATRICS
49. A child of diabetes mellitus with toxic features of dehydration, high-grade fever 102°F, low BP, tachycardia with elevated blood sugar. Immediate management is:
  • a. NS
  • b. Steroids
  • c. IV antibiotic
  • d. IV insulin and dextrose
Correct Answer: a
50. Delayed puberty in females is said to be present when there is no menarche by the age of:
  • a. 16 years
  • b. 15 years
  • c. 14 years
  • d. 13 years
Correct Answer: b
51. A child with multiple episodes of diarrhea is presented in the emergency department. His lab values are Na 125 mEq/L, K 2.3 mEq/L, and pH 7.2. The best fluid management for this condition is with:
  • a. 10% dextrose
  • b. 3% hypertonic saline
  • c. Normal saline
  • d. N/3 sodium + 5% Dextrose
Correct Answer: c
52. A 2-year-old child presented 2 hours after accidentally swallowing an ear implant battery of his mother which was lodged in the esophagus. The best management is:
  • a. Wait for spontaneous passage
  • b. Endoscopic removal
  • c. Laparotomy
  • d. No need to worry
Correct Answer: b
53. Which is elevated in breastfeeding jaundice?
  • a. Unconjugated bilirubin
  • b. Monoglucuronide
  • c. Diglucuronide
  • d. Delta bilirubin
Correct Answer: a
54. Which structure is involved in RDS in neonates?
  • a. Type I pneumocytes
  • b. Type II pneumocytes
  • c. Alveolar macrophages
  • d. Clara cells
Correct Answer: b
55. The most likely underlying condition in children with recurrent UTI is:
  • a. Vesicoureteral reflux
  • b. Renal stones
  • c. Ectopic ureter
  • d. Posterior urethral valve
Correct Answer: a
56. A 10-year-old child with icterus, fever, and abdominal pain had a history of vomiting for 5 days. He now becomes drowsy suddenly for an hour. What needs to be done immediately?
  • a. Electrolytes
  • b. Bedside USG
  • c. Liver enzyme
  • d. Bedside blood glucose
Correct Answer: d
57. Sensitive marker of suspected spinal defect in a child:
  • a. Alpha fetoprotein
  • b. LDH
  • c. Inhibin A
  • d. Alkaline phosphatase
Correct Answer: a
58. A child presented to the emergency department with toxic features. He has low BP and tachycardia. He was diagnosed with tonsillitis. What is your immediate next step?
  • a. Fluid resuscitation
  • b. IV antibiotic
  • c. Steroid
  • d. Tonsillectomy
Correct Answer: a
59. Which of the following criteria is diagnostic for bronchial asthma?
  • a. FEV1 > 15% increase following 6 minutes of exercise
  • b. FEV1 > 15% increase following bronchodilator administration
  • c. FEV1 less than 12 percentage rise with bronchodilator
  • d. No change in FEV1 following bronchodilator administration
Correct Answer: b
60. Rescue breath in children prior to chest compressions is given because:
  • a. Neonatal distress is mostly due to hypoxia
  • b. Neonatal distress is mostly due to cardiac cause
  • c. Rescue breaths help to open up the lungs
  • d. Neonatal distress is mostly due to idiopathic causes
Correct Answer: a
ORTHOPEDICS
61. Perthes' disease is most common in the age group of:
  • a. 1-4 years
  • b. 4-8 years
  • c. 8-10 years
  • d. 11-14 years
Correct Answer: b
62. 84-year-old elderly patient with history of an intertrochanteric fracture following a trivial trauma. Why is surgical treatment required?
  • a. Early mobilization
  • b. Early healing
  • c. To prevent non-union
  • d. Surgery is rather avoided in this age group
Correct Answer: a
63. A 10-year-old presented in PHC with a history of falling from a tree with an outstretched hand. X-ray shows fracture of middle 1/3rd clavicle which was displaced and overlapped. Which is the best management of the case?
  • a. Analgesic, apply splintage and refer to higher center
  • b. Figure of 8 bandage as a definitive treatment
  • c. Meneva cast
  • d. K-wire fixation under ketamine
Correct Answer: b
64. A pregnant lady complained of sensory loss in her right thumb, index finger, and half-ring finger. Which nerve may be affected?
  • a. Ulnar nerve
  • b. Musculocutaneous nerve
  • c. Median nerve
  • d. Axillary nerve
Correct Answer: c
65. Following a humerus fracture, a patient had a wrist drop. The affected nerve is:
  • a. Ulnar nerve
  • b. Axillary nerve
  • c. Radial nerve
  • d. Musculocutaneous nerve
Correct Answer: c
66. The earliest sign of compartment syndrome is:
  • a. Pain out of proportion
  • b. Pallor
  • c. Paresthesia
  • d. Pulselessness
Correct Answer: a
67. The best prognosis for nerve injury is seen with:
  • a. Neuropraxia
  • b. Axonotmesis
  • c. Neurotmesis
  • d. Axonopraxia
Correct Answer: a
68. Soap bubble appearance is seen in:
  • a. Giant cell tumor
  • b. Ewing sarcoma
  • c. Osteosarcoma
  • d. Osteoid osteoma
Correct Answer: a
69. An elderly patient presented with multiple fractures. Her serum calcium level is 11.5 mg/dL, PO4 is 2.5 mg/dL and ALP is 940 IU/L. What is the most probable diagnosis?
  • a. Hyperparathyroidism
  • b. Osteomalacia
  • c. Osteoporosis
  • d. Multiple myeloma
Correct Answer: a
70. Which of the following complications can be attributed to rib fractures?
  • a. Hemothorax
  • b. Abscess formation
  • c. Chylothorax
  • d. Pleural effusion
Correct Answer: a
ENT
71. A middle-aged woman has a conductive hearing loss in PTA with normal TM. What is the next line of investigation?
  • a. Tympanometry
  • b. Acoustic reflex
  • c. OAE
  • d. BERA
Correct Answer: a
72. Most common malignant tumor of the submandibular gland is:
  • a. Pleomorphic adenoma
  • b. Adenoid cystic carcinoma
  • c. Squamous cell carcinoma
  • d. Mucoepidermoid carcinoma
Correct Answer: d
73. A 12-year-old girl has an alleged history of slap on the cheek due to which her tympanic membrane was ruptured 50%. Best treatment is:
  • a. Myringoplasty
  • b. Prevent water entry and let it heal on its own
  • c. Antibiotic ear drops
  • d. Steroids
Correct Answer: b
74. A case of epistaxis from Little's area was initially managed with chemical cautery. The bleeding was not controlled. What is the next line of management?
  • a. Wait and watch
  • b. Anterior nasal packing
  • c. Anterior and Posterior Nasal Packing
  • d. Sphenopalatine ligation
Correct Answer: c
75. A 75-year-old male complained of recurrent nasal bleeding. Most common site of epistaxis in this patient is:
  • a. Woodruff's plexus
  • b. Little's area
  • c. Columellar vein
  • d. Superior labial artery
Correct Answer: a
76. A child with toxic features of dehydration and a high-grade fever of 102°F. Soft tissue lateral view X-ray of the neck shows increased prevertebral space. This is suggestive of:
  • a. Parapharyngeal abscess
  • b. Retropharyngeal abscess
  • c. Peritonsillar abscess
  • d. Ludwig's angina
Correct Answer: b
77. Marker of CSF rhinorrhea is:
  • a. Alpha 1 transferrin
  • b. Alpha2 transferrin
  • c. Beta 1 transferrin
  • d. Beta 2 transferrin
Correct Answer: d
78. A 30-year-old male, teacher by profession complaints of sustained vertigo, tinnitus of 7 days duration with severe SNHL. What is the most likely diagnosis?
  • a. Acute labyrinthitis
  • b. Meniere's disease
  • c. BPPV
  • d. Vestibular Neuronitis
Correct Answer: a
79. A 40-year-old male had an alleged history of temporal bone fracture with Grade IV facial palsy presented 2 days after the episode. What is the earliest best treatment?
  • a. High-dose steroid
  • b. Facial nerve decompression
  • c. Electromyography
  • d. Neuronography
Correct Answer: b
80. A 21-year-old sexually active woman with a painful ulcer over the lower lip, recurrent, and mostly during the menstrual cycle. What is the likely diagnosis?
  • a. Syphilis
  • b. Aphthous stomatitis
  • c. Carcinoma lip
  • d. Herpes labialis
Correct Answer: b
OPHTHALMOLOGY
81. Unwanted growth of eyelashes is associated with which anti-glaucoma drug?
  • a. PG analogues
  • b. Beta-blockers
  • c. Anticholinergic drugs
  • d. Carbonic anhydrase inhibitors
Correct Answer: a
82. Earliest characteristic finding in glaucoma is:
  • a. Ring scotoma
  • b. Paracentral scotoma
  • c. Central scotoma
  • d. Centrocecal scotoma
Correct Answer: b
83. Direct Ophthalmoscope magnification is:
  • a. 5 times
  • b. 10 times
  • c. 15 times
  • d. 20 times
Correct Answer: c
84. A 50-year-old male was examined in ophthalmology OPD. He had findings of flame-shaped hemorrhage, arteriolar attenuation, and cotton wool spots. The most probable diagnosis is:
  • a. Diabetic retinopathy
  • b. Hypertensive retinopathy
  • c. Trauma
  • d. Macular degeneration
Correct Answer: b
85. Maximum refraction of light is done by:
  • a. Cornea
  • b. Lens
  • c. Vitreous humour
  • d. Aqueous humour
Correct Answer: a
86. Regardless of the etiology of the corneal ulcer, which drug is given to all patients?
  • a. Cycloplegics
  • b. Antibiotics
  • c. Antifungals
  • d. Steroids
Correct Answer: a
87. Diagnosis of a primary open-angle glaucoma is done by observing:
  • a. Anterior chamber angle
  • b. Optic disc
  • c. Retina
  • d. Lens
Correct Answer: a
ANESTHESIA
88. Level of block in spinal anesthesia by Hyperbaric Bupivacaine depends upon:
  • a. Position of the patient
  • b. Dose of the drug
  • c. Addition of other drugs
  • d. Barbotage
Correct Answer: a
89. Mallampati grading is used to assess:
  • a. Intubation
  • b. Airway
  • c. Risk of aspiration
  • d. Dose of inhaled anesthetic agent
Correct Answer: b
90. Cannot intubate cannot ventilate. What is your next immediate approach?
  • a. Open tracheostomy
  • b. Scalpel Cricothyrotomy
  • c. Percutaneous tracheostomy
  • d. LMA
Correct Answer: b
91. Hypoxemia is present when PaO2 is below:
  • a. 90 mm Hg
  • b. 80 mm Hg
  • c. 70 mm Hg
  • d. 60 mm Hg
Correct Answer: d
92. 10 units of packed cells were transfused in a patient. Massive blood transfusion causes:
  • a. Hyperkalemia, hypocalcemia
  • b. Hyperkalemia, hypercalcemia
  • c. Hypokalemia, hyponatremia
  • d. Hypokalemia, hypocalcemia
Correct Answer: a
93. Which of the following is an inodilator?
  • a. Dopamine
  • b. Dobutamine
  • c. Adrenaline
  • d. Noradrenaline
Correct Answer: b
94. Which type of hemorrhage is seen in the first 24 hours post-operative period?
  • a. Primary
  • b. Secondary
  • c. Tertiary
  • d. Reactionary
Correct Answer: d
PSYCHIATRY
95. Which one of the following will have the highest risk of suicide?
  • a. Mood disorders
  • b. Psychotic disorders
  • c. Anxiety disorders
  • d. Alcoholism
Correct Answer: a
96. A patient who previously used to consume alcohol was admitted to the ICU. This morning the patient had confusion, tremors, and irrelevant talks. The most likely diagnosis is:
  • a. Delirium
  • b. Wernicke-Korsakoff syndrome
  • c. Psychosis
  • d. Schizophrenia
Correct Answer: a
97. A patient has OCD with predominant obsessions. He doesn't want pharmacotherapy. What is the preferred non-pharmacological treatment in this case?
  • a. Exposure and response prevention
  • b. Response prevention
  • c. Systematic desensitization
  • d. Thought blocking
Correct Answer: a
98. A person was scolded in the office by his boss. He goes home and is nasty to his wife. What is the defense mechanism?
  • a. Displacement
  • b. Sublimation
  • c. Rationalisation
  • d. Transference
Correct Answer: a
99. A patient after RTA is unable to recall events prior to the accident. This is best termed as:
  • a. Anterograde amnesia
  • b. Retrograde amnesia
  • c. Confabulation
  • d. Dissociative amnesia
Correct Answer: b
100. A 12-year-old girl has multiple fainting episodes lasting for up to 30 minutes, with stiffening of her body. There are no injuries and the episodes never occur during sleep. No bowel or bladder incontinence. Most likely diagnosis is:
  • a. Conversion disorder
  • b. Malingering
  • c. Factitious disorder
  • d. Seizure disorder
Correct Answer: a
101. A patient took Haloperidol 10 mg for one day from the local pharmacy due to anxiety and tension. She presented with protruded tongue since last night and she is unable to retract her tongue back. What is the likely cause?
  • a. Extrapyramidal symptoms
  • b. Haloperidol overdose
  • c. Conversion disorder
  • d. Akathisia
Correct Answer: a
RADIOLOGY
102. The minimum duration of fasting before hepatobiliary USG is:
  • a. 4 hours
  • b. 6 hours
  • c. 8 hours
  • d. 10 hours
Correct Answer: b
103. A 25-year-old lactating female with a soft painful breast mass visited OPD. The investigation of choice in this case is:
  • a. Mammography
  • b. USG
  • c. CT
  • d. FNAC
Correct Answer: b
104. X-ray abdomen shows gas in both the inside and outside walls of the intestine. The likely diagnosis is:
  • a. Intussusception
  • b. Pneumoperitoneum
  • c. Obstruction
  • d. PUD
Correct Answer: b
105. The best way to prevent contrast-induced nephropathy is:
  • a. Hydration with normal saline
  • b. N-acetyl cysteine
  • c. Fenoldopam
  • d. Hemodialysis
Correct Answer: a
106. Hounsfield unit of zero is seen in:
  • a. Fat
  • b. Air
  • c. Water
  • d. Bone
Correct Answer: c
107. Which investigation helps to visualize the terminal ileum?
  • a. Barium meal
  • b. Barium swallow
  • c. Barium follow through
  • d. Barium enema
Correct Answer: c
108. Bat wing appearance of pulmonary edema in X-ray is a classic finding associated with:
  • a. Congestive heart failure
  • b. Interstitial lung disease
  • c. Renal failure
  • d. Liver cirrhosis
Correct Answer: a
DERMATOLOGY
109. A 52-year-old male presented with frontal and temporal loss of hair. On further asking, he said his uncle also had a similar pattern of hair loss. The most likely diagnosis is:
  • a. Androgenetic alopecia
  • b. Telogen effluvium
  • c. Tinea capitis
  • d. Alopecia areata
Correct Answer: a
110. A patient has plaques with silvery scales over the extensor surface knee, and elbow. These features are seen in:
  • a. Psoriasis
  • b. Lichen planus
  • c. Leprosy
  • d. SLE
Correct Answer: a
111. A 50-year-old man presents to the dermatology OPD with clear multiple patches of hair loss. An exclamation mark sign is seen. What is the treatment?
  • a. Wait and watch for spontaneous resolution
  • b. Intralesional steroids
  • c. Topical minoxidil
  • d. Topical antifungal
Correct Answer: b
112. A 60 years old man presented with multiple fluid-filled lesions on the trunk with excoriation and crusting. The hemorrhagic fluid-filled lesions burst open themselves in 2-3 days. Likely diagnosis:
  • a. Bullous pemphigoid
  • b. Pemphigus vulgaris
  • c. Epidermolysis bullosa
  • d. Linear IgA disease
Correct Answer: b
113. Vitiligo is caused due to:
  • a. Focal loss of melanocytes
  • b. Decreased biosynthesis of melanin
  • c. Sunburn
  • d. Radiation exposure
Correct Answer: a
114. Specific finding which is characteristic of atopic dermatitis:
  • a. Family history of hay fever/Asthma
  • b. Onset within 2 years of age
  • c. Dry skin
  • d. Extreme pruritus
Correct Answer: a
115. What is the causative agent of tinea versicolor?
  • a. Malassezia furfur
  • b. Sporotrichosis
  • c. HHV 7
  • d. EBV
Correct Answer: a
ANATOMY
116. A patient presents with dental caries with referred pain to the ear. Which nerve is likely involved?
  • a. Glossopharyngeal nerve
  • b. Trigeminal nerve
  • c. Facial nerve
  • d. Vagus nerve
Correct Answer: b
117. The spinal cord ends at the L1 level. Nerve roots below this level are present as:
  • a. Filum terminale
  • b. Cauda equina
  • c. Subarachnoid space
  • d. Coccyx
Correct Answer: b
118. A 38-year-old man was diagnosed with external hemorrhoids. He has pain during defecation. The pain is carried by:
  • a. Pudendal nerve
  • b. Pelvic splanchnic nerve
  • c. Genitofemoral nerve
  • d. Inferior mesenteric nerve
Correct Answer: a
119. All are accessory GI organs EXCEPT:
  • a. Liver
  • b. Spleen
  • c. Pancreas
  • d. Gallbladder
Correct Answer: b
120. Blood supply distribution of the liver is:
  • a. 90% portal vein and 10% hepatic artery
  • b. 90% hepatic artery and 10% portal vein
  • c. 75% portal vein and 25% hepatic artery
  • d. 75% hepatic artery and 25% portal vein
Correct Answer: c
121. Which is the major support of the cervical portion of the uterus?
  • a. Transverse cervical ligament
  • b. Broad ligament
  • c. Uterosacral ligament
  • d. Round ligament
Correct Answer: a
122. Which of the following is not a content of femoral sheath?
  • a. Femoral nerve
  • b. Femoral vein
  • c. Deep inguinal lymph nodes
  • d. Femoral artery
Correct Answer: a
123. Preganglionic fibers of submandibular glands are supplied by:
  • a. Otic ganglion
  • b. Superior salivatory nucleus
  • c. Inferior salivatory nucleus
  • d. Sublingual ganglion
Correct Answer: b
124. All are Rotator cuff muscles EXCEPT:
  • a. Supraspinatus
  • b. Infraspinatus
  • c. Teres minor
  • d. Teres major
Correct Answer: d
125. Obscurity of the right heart border is evident on X-ray. Consolidation is seen on which lobe of the lung?
  • a. Medial segment of right middle lobe
  • b. Lower segment of right upper lobe
  • c. Superior segment of right lower lobe
  • d. Posterior segment of right lower lobe
Correct Answer: a
126. A patient had painful vesicles over the right forehead and right side of the nose. Involvement of which nerve will lead to blindness?
  • a. Trigeminal
  • b. Optic
  • c. Oculomotor
  • d. Trochlear
Correct Answer: a
127. Cartwheel appearance of the nucleus is seen in:
  • a. Plasma cell
  • b. Lymphocytes
  • c. Monocytes
  • d. Mast Cell
Correct Answer: a
PHYSIOLOGY
128. Least immunogenic for an organ transplantation is:
  • a. Liver
  • b. Kidney
  • c. Lung
  • d. Heart
Correct Answer: a
129. ADH is mainly released in response to:
  • a. Serum sodium level
  • b. Urine osmolality
  • c. Serum osmolality
  • d. Hypovolemia
Correct Answer: c
130. Major regulator of cerebral blood flow in the ischemic part of the brain is by:
  • a. Intracranial pressure
  • b. Oxygen
  • c. Mean Arterial Pressure
  • d. Cerebral perfusion pressure
Correct Answer: d
131. A person went to Namche bazaar. After acclimatization, the earliest parameter that returns to normal will be:
  • a. Bicarbonate
  • b. RBC
  • c. Cardiac Output
  • d. Oxygen
Correct Answer: d
132. An adult male has a respiratory rate of 12/hr, a tidal volume of 600 mL, and a dead space of 150 mL. Calculate the alveolar ventilation.
  • a. 5.4 L/min
  • b. 7.2 L/min
  • c. 6 L/min
  • d. 9 L/min
Correct Answer: a
133. In moderate exercise, the respiratory rate is increased due to the response of:
  • a. Proprioception receptor in joints
  • b. Increased pCO2 in arterial blood
  • c. Increased PO2 in arterial blood
  • d. J receptor stimulation
Correct Answer: a
134. A healthy, 25-year-old male participates in a 10 km marathon. Which of the following muscles are involved in expiration with labored breathing?
  • a. Diaphragm and external intercostals
  • b. Diaphragm and internal intercostals
  • c. Diaphragm only
  • d. Internal intercostal and abdominal recti
Correct Answer: d
135. Total peripheral resistance is increased by:
  • a. Alpha 1 receptor
  • b. Alpha 2 receptor
  • c. Beta 1 receptor
  • d. Beta 2 receptor
Correct Answer: a
136. Which of the following components is absent in cryoprecipitate?
  • a. Fibrinogen
  • b. Factor VIII
  • c. vWF
  • d. Antithrombin III
Correct Answer: d
137. Pain and temperature of the contralateral body are carried by which fiber?
  • a. Anterior spinothalamic tract
  • b. Lateral lemniscus
  • c. Spinal lemniscus
  • d. Medial lemniscus
Correct Answer: c
138. Goosebumps are due to reflex mediated by which layer of the skin?
  • a. Stratum corneum
  • b. Stratum spinosum
  • c. Papillary dermis
  • d. Reticular dermis
Correct Answer: c
139. A 40-year-old patient had pituitary resection surgery. Which function of the adrenal gland will be preserved in the immediate post-operative period?
  • a. Morning peak of cortisol
  • b. Aldosterone function
  • c. Water retention in response to hypovolemia
  • d. Mid-day peak of cortisol
Correct Answer: b
PATHOLOGY
140. Factor VIII deficiency in severe hemophilia is:
  • a. <1%
  • b. 2-5%
  • c. 5-10%
  • d. >10%
Correct Answer: a
141. Auer rods are present in:
  • a. CLL
  • b. CML
  • c. AML
  • d. ALL
Correct Answer: c
142. A patient presents with recurrent bleeding. On investigation, platelet count, PT, and aPTT were normal. The most likely diagnosis is:
  • a. Immune thrombocytopenic purpura
  • b. vWD
  • c. Hemophilia A
  • d. DIC
Correct Answer: b
143. Esophageal columnar metaplasia is a characteristic feature of:
  • a. Barrett's esophagus
  • b. Mallory-Weiss tear
  • c. Boerhaave syndrome
  • d. Diaphragmatic hernia
Correct Answer: a
144. Autoantibodies against Ach Receptor at the neuromuscular junction is a characteristic pathology of:
  • a. Lambert Eaton syndrome
  • b. Rheumatoid arthritis
  • c. Myasthenia gravis
  • d. Multiple myeloma
Correct Answer: c
145. Which of the following is a risk factor for tumor lysis syndrome?
  • a. Anemia
  • b. Hyperleukocytosis
  • c. Leucopenia
  • d. Thrombocytopenia
Correct Answer: b
146. Leukotrienes are derived from:
  • a. Endothelial cell
  • b. Mast cell
  • c. Monocytes
  • d. Macrophages
Correct Answer: b
147. FNAC was done for a thyroid swelling in a 22-year-old female. The result is most likely to represent:
  • a. Papillary carcinoma
  • b. Follicular carcinoma
  • c. Anaplastic carcinoma
  • d. Medullary carcinoma
Correct Answer: a
148. Urinary retention is seen in the case of BPH. The most commonly involved lobe in BPH is:
  • a. Anterior
  • b. Lateral
  • c. Median
  • d. Posterior
Correct Answer: c
149. A patient with pneumonia has cyanosis of the fingers. What is the most likely cause of anemia?
  • a. Histotoxic hypoxia
  • b. Stagnant hypoxia
  • c. Anemic hypoxia
  • d. Hypoxic hypoxia
Correct Answer: d
PHARMACOLOGY
150. Dose adjustment of Amphotericin B is done in:
  • a. Renal failure
  • b. Hepatic failure
  • c. Rashes
  • d. Obstructive pulmonary diseases
Correct Answer: a
151. Tranexamic acid used to control:
  • a. Bleeding
  • b. Infection
  • c. Fever
  • d. Pain
Correct Answer: a
152. Which of the antianginal/antiarrhythmic drugs causes reflex tachycardia as a side effect?
  • a. Nifedipine
  • b. Amlodipine
  • c. Verapamil
  • d. Diltiazem
Correct Answer: a
153. A patient under ACE inhibitor medication complained of dry cough. The reason for the side effect is:
  • a. Decreased degradation of bradykinin
  • b. Increased degradation of bradykinin
  • c. Increased histamine release
  • d. Decreased histamine release
Correct Answer: a
154. Drugs given to prevent motion sickness is:
  • a. Hyoscine
  • b. Metoclopramide
  • c. Ondansetron
  • d. Chlorpromazine
Correct Answer: a
155. Which of the following anti-arrhythmic drugs contains iodine and causes thyrotoxicosis?
  • a. Amiodarone
  • b. Lignocaine
  • c. Procainamide
  • d. Flecainide
Correct Answer: a
156. The main reason for avoiding the combined administration of levodopa and an inhibitor of monoamine oxidase is to prevent:
  • a. Respiratory depression
  • b. Hypertensive crisis
  • c. Acute psychotic reaction
  • d. Cardiovascular collapse and CNS depression
Correct Answer: b
157. Mechanism of Action of cyclophosphamide:
  • a. DNA alkylation
  • b. Inhibition of microtubules formation
  • c. Inhibits DNA synthesis
  • d. DHFR inhibitor
Correct Answer: a
158. A cancer patient is on methotrexate therapy. Urinary alkalization needs to be done. What is the rationale behind this?
  • a. Decrease tubular secretion
  • b. Increases reabsorption
  • c. It is a weak acid
  • d. It is a weak base
Correct Answer: c
159. Action of Pilocarpine on the pupil is:
  • a. Miosis
  • b. Mydriasis
  • c. No change
  • d. Irregular pupil
Correct Answer: a
BIOCHEMISTRY
160. Vit B12 deficiency diagnosis can be done by urine analysis by the measurement of:
  • a. Urinary methylmalonic acid
  • b. Homocysteine level
  • c. Formiminoglutamic acid
  • d. Branched-chain keto acids
Correct Answer: a
161. An icteric patient with urobilinogen in urine but absent bilirubin. This is a significant finding of:
  • a. Hemolytic jaundice
  • b. Rotor syndrome
  • c. Dubin Johnson syndrome
  • d. Autoimmune hepatitis
Correct Answer: a
162. Hemoglobin and myoglobin can be differentiated on the basis of molecular size by:
  • a. Gel electrophoresis
  • b. Gel filtration chromatography
  • c. Ion exchange chromatography
  • d. Thin layer chromatography
Correct Answer: b
163. Glucose-6-Phosphate to 6-Phosphogluconolactone in the HMP pathway is carried out by the enzyme:
  • a. Glucokinase
  • b. Gluconolactonase
  • c. Hexokinase
  • d. Glucose-6-phosphate dehydrogenase
Correct Answer: d
164. Mutation leading to stop codon:
  • a. Nonsense mutation
  • b. Missense mutation
  • c. Frameshift mutation
  • d. Translocation
Correct Answer: a
165. A lady presents with anemia which was associated with brittle spoon-shaped nails, and hair loss. She follows a strict vegan diet. What is the likely cause?
  • a. Iron deficiency
  • b. Vitamin B12 deficiency
  • c. Folic acid deficiency
  • d. Vitamin D deficiency
Correct Answer: a
166. Which of the following is the cause of death in CO poisoning that is the most dangerous mechanism for death?
  • a. Oxygen displacement from Hb
  • b. Formation of complex compound
  • c. Inhibition of cytochrome oxidase
  • d. Decreased oxygen concentration
Correct Answer: a
167. In which of the following conditions, there is maximum absorption of alcohol?
  • a. When taken with food rich in carbohydrate
  • b. When taken with protein-rich food
  • c. When taken with fatty food
  • d. When taken with carbonated beverages
Correct Answer: d
MICROBIOLOGY
168. You are working in a PHC. What is used for rapid diagnosis that is the fastest and most sensitive test for diagnosis of tuberculosis?
  • a. Gene X-pert
  • b. Chest X-ray
  • c. Mantoux test
  • d. ZN staining
Correct Answer: a
169. E. coli is not flushed by urine because of:
  • a. Capsule
  • b. Polysaccharide
  • c. Flagella
  • d. Fimbriae
Correct Answer: d
170. Which among the following is used to stain malarial parasites?
  • a. Gram stain
  • b. Albert stain
  • c. Giemsa stain
  • d. Malachite green stain
Correct Answer: c
171. Media used to differentiate between lactose fermenter and non fermenters is:
  • a. Nutrient agar
  • b. MacConkey agar
  • c. Chocolate agar
  • d. Deoxycholate citrate agar
Correct Answer: b
172. Natural active immunity is received from:
  • a. Breastfeeding
  • b. Mother to fetus
  • c. Immunization
  • d. Immunity after infection and recovery
Correct Answer: d
173. Most commonly used method of antibiotic sensitivity testing is based on:
  • a. Culture media
  • b. Disc diffusion
  • c. Tube culture
  • d. Broth
Correct Answer: b
174. Spores can be killed by:
  • a. Heat
  • b. Boiling at 100°C
  • c. Pasteurization
  • d. Autoclave
Correct Answer: d
175. Which form of Plasmodium is transferred from the mosquito to the human?
  • a. Merozoite
  • b. Hypnozoite
  • c. Sporozoite
  • d. Gametocyte
Correct Answer: c
COMMUNITY MEDICINE
176. The purpose of random assignment in clinical trials is:
  • a. Facilitate double blinding
  • b. To reduce selection bias in the allotment of treatment
  • c. Ensure that the groups are comparable on baseline characteristics
  • d. Help ensure the study subjects are representative of the general population
Correct Answer: b
177. Which vaccine causes thrombocytopenia?
  • a. MMR
  • b. Influenza
  • c. Typhoid
  • d. Pneumococcal conjugate vaccine
Correct Answer: a
178. Diagnostic power of a screening test is reflected by:
  • a. Sensitivity
  • b. Specificity
  • c. Positive predictive value
  • d. Negative predictive value
Correct Answer: c
179. A medical recorder collected a sample of data regarding total deaths due to RTA, total cases of cholera, total cases of AIDS, total cases of measles, and number of drug addicts. The data is best termed as:
  • a. Mortality data
  • b. Morbidity data
  • c. Health-related data
  • d. Disability data
Correct Answer: c
180. Early Warning and Reporting System (EWARS) in Nepal is:
  • a. Individual case-based reporting system
  • b. Community-based reporting system
  • c. Physician-based reporting system
  • d. Hospital-based patient reporting
Correct Answer: d
181. Total Fertility Rate of a country is 2.5. What does it signify?
  • a. Population is slowly growing
  • b. Population is rapidly growing
  • c. Population growth is static
  • d. Population growth is explosive
Correct Answer: a
182. A randomized control trial was done on prisoners. Which is the most accurate?
  • a. No need to take consent as they are prisoners
  • b. They have equal rights like other people
  • c. Prisoners cannot included in the trial
  • d. They have rights different than those of normal people
Correct Answer: b
183. You are giving awareness in a Community. One person asked about the risk factors for developing asthma. Least risk of occupational asthma is seen with:
  • a. Steel factory worker
  • b. Baker
  • c. Shoemaker
  • d. Hairdresser
Correct Answer: c
184. A newly married woman with a history of irregular menstruation comes for contraception counseling. She plans to have a baby only after 1 year. What is the appropriate method of contraception?
  • a. Barrier methods
  • b. OCP
  • c. Emergency contraceptive pills
  • d. IUCD
Correct Answer: b
185. What is the duration of prophylaxis for patients of rheumatic fever with carditis without residual valvular heart disease?
  • a. 5 years or until 21 years of age
  • b. 5 years or until 40 years of age
  • c. 10 years or until 40 years of age
  • d. 10 years or until 21 years of age
Correct Answer: d
FORENSIC MEDICINE
186. Organophosphate poisons are exceptionally prone to be stored in:
  • a. Muscle
  • b. Liver
  • c. Lymph node
  • d. Fat
Correct Answer: d
187. Insecticide safe to use in the kitchen is:
  • a. Malathion
  • b. Parathion
  • c. Sodium hypochlorite
  • d. Abate
Correct Answer: c
188. Unconscious patient was brought to the emergency without relatives. The operating surgeon performed emergency surgery as no one was there to give consent. This represents:
  • a. Therapeutic privilege
  • b. Implied consent
  • c. Therapeutic waiver
  • d. Informed consent
Correct Answer: b
189. Acrodynia is caused by poisoning due to:
  • a. Mercury
  • b. Lead
  • c. Arsenic
  • d. Iron
Correct Answer: a
190. First muscle to be involved in rigor mortis is:
  • a. Masseter
  • b. Flexors
  • c. Myocardium
  • d. Extensors
Correct Answer: c
CPD (Clinical/Personal Development)
191. Which of the following best prevents the irrational use of drugs?
  • a. Follow standard treatment guidelines
  • b. No need for a doctor's prescription
  • c. Mass treatment
  • d. Over-the-counter drugs
Correct Answer: a
192. Unresponsive child while resuscitation develops tension pneumothorax. What is your immediate response?
  • a. Needle decompression
  • b. Chest tube insertion
  • c. X-ray
  • d. Send for CT scan
Correct Answer: a
193. A patient after a road traffic accident presented with tension pneumothorax. What is immediate management?
  • a. Needle decompression in second intercostal space
  • b. Immediate chest X-ray
  • c. CT scan
  • d. Emergency thoracotomy
Correct Answer: a
194. Communication skill is planned to be included in the medical curriculum. What do you think about this?
  • a. Communication skill is gradually learned with experience
  • b. Communication skills cannot be taught via curriculum
  • c. Communication skills are not that important
  • d. It is not a basic clinical skill
Correct Answer: a
195. Truth-telling is based on the principle of:
  • a. Autonomy
  • b. Beneficence
  • c. Informed consent
  • d. Confidentiality
Correct Answer: a
196. In health management, good managers are those who ensures use the resources appropriately with no wastage. This is best represented as:
  • a. Efficiency
  • b. Effectiveness
  • c. Resourcefulness
  • d. Objective
Correct Answer: a
197. An unresponsive child was presented to the ER. He was pulseless on all peripheral arteries. ECG has normal QRS in the monitor. All are components of treatment for the child EXCEPT:
  • a. Calcium gluconate
  • b. Adrenaline
  • c. Synchronized DC shock
  • d. CPR
Correct Answer: c
198. You want to swiftly decrease the temperature of the body for a patient with high-grade fever. The most effective method for decreasing external temperature is:
  • a. 1 gm IV paracetamol
  • b. Sponging with tepid water
  • c. Cold sponging with ice water
  • d. Fanning the room
Correct Answer: a
199. At a family party, a child eats peanut butter. After some time, he presented with diarrhea, vomiting, and acute onset of shortness of breath. Which is the best immediate management?
  • a. IM adrenaline
  • b. IV diphenhydramine
  • c. Corticosteroids
  • d. Salbutamol
Correct Answer: a
200. The Department of Drug Administration works for the promotion of rational drug use by healthcare workers. It comes under which of the following strategies?
  • a. Regulatory strategy
  • b. Educational and training
  • c. Promotion of traditional medicines
  • d. Drug Management
Correct Answer: a

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